Experimental retinal detachment was attempted in albino rabbits by the injection of hyaluronidase (2 TRU) between the retina and vitreous body.
Retinal detachment was successfully induced in 12 eyes(62. 5%) after 1-4 days.
Hyaluronidase injection, combined with mechanical injuries of the retina produced retinal detachment, in 5 eyes(60. 0%).
When the retinal detachment was produced, amplitudes of the a-and b-waves decreased, maximum reduction being 41.6%(a-wave) and 34.5%(b-wave). Ten to 14 days after the treatment ERG waves began to increase gradually. ERG waves rose slightly in cases in which no detachment had been successfully produced
|